Abstract
Rheumatoid arthritis (RA) is a chronic autoimmune disorder that causes inflammation in the joints, but it can also impact various other areas of the body, such as lungs, heart and skin. It was observed that clinicians use the Ayurveda formulations for the management of different arthritic problems. Rumogin 5 capsules were developed by the medical experts at Planet Ayurveda to keep the joints healthy and alleviate pain and stiffness in individuals with rheumatoid arthritis. Rumogin 5 is formulated with a blend of several herbs, including, Sonth (Zingiber officinale), Haridra (Curcuma longa), Maricha (Piper nigrum), Shallaki (Boswellia serrata) and Pippali (Piper longum). These herbs have anti-inflammatory, anti-arthritic, analgesic and antioxidant qualities, which enhances joint flexibility and provide significant benefits for individuals with Rheumatoid arthritis. A clinical study was carried out at Planet Ayurveda for two months, involving 40 patients who were divided into two groups of 20 each, to assess the effectiveness of Rumogin 5 in managing rheumatoid arthritis. It was concluded that RA can be well managed with Rumogin 5 without any side effects. The clinical data of this study reveals that Rumogin 5 was effective in most of the signs and symptoms of the RA disease at an extremely significant level. Rumogin 5 proved to be a better approach to improve quality of life in an RA affected patient.
Introduction
Rheumatoid arthritis (RA) is a persistent autoimmune disorder, recognized as a chronic condition that primarily affects the joints. It causes persistent inflammation, leading to pain, swelling, redness and stiffness. Over time, this condition can reduce the range of motion and cause damage to the joints. RA is a systemic disease and can affect other parts of the body as well. Chronic inflammation of the joints eventually results in joint damage, causing the breakdown of cartilage and erosion of bone. RA is more common among women than in men, and is most often seen in older adults. RA is considered as early when symptoms last for less than six months, while it is classified as established RA when symptoms persist for more than six months. The disease often affects the hands, knees or ankles, typically impacting the same joints on both sides of the body, such as both hands and both knees. If left untreated, RA is a progressive condition that can lead to deterioration of health and an increased risk of mortality. RA lacks a specific laboratory test to identify the disease, which makes it difficult to diagnose, especially in the early stages.
Common Sign And Symptoms Of Rheumatoid Arthritis
- Joint pain, swelling, stiffness and tenderness in the joints
- Increased warmth around the affected joints
- Severe tiredness or exhaustion
- Low-grade fever
- Low appetite
- Stiffness in the morning lasting for 30 minutes or longer
- Rheumatoid nodules, which are small lumps beneath the skin
The goals of managing rheumatoid arthritis are to alleviate pain and swelling, slow the progression of the disease, prevent disability and improve overall quality of life. Ayurveda is a traditional system of medicine that is commonly practised in India, in the treatment of patients with RA for many decades. So there is a need for a clinical approach which is essential for diagnosing the condition and preventing severe joint damage. The present study was undertaken to assess the effectiveness and safety of Ayurvedic formulation i.e. Rumogin 5 capsules. It is composed of several herbs, including, Shallaki (Boswellia serrata), Sonth (Zingiber officinale), Haridra (Curcuma longa), Maricha (Piper nigrum) and Pippali (Piper longum). These herbs possess anti-inflammatory, antioxidant and analgesic properties, and have proven to be beneficial for individuals with rheumatoid arthritis.
Study Objective
To evaluate the effectiveness and safety of Ayurvedic treatment; Rumogin 5; as a potential approach to enhancing the quality of life in patients affected by Rheumatoid arthritis (RA).
Raw Materials
Herbs used in Rumogin 5 capsules are as follows in table 1:
Table 1 Herbs Used
| S.No. | Herb | Latin Name | Part Used | Quantity |
|---|---|---|---|---|
| 1 | Sonth | Zingiber officinale | Rhizome | 150 mg |
| 2 | Haridra | Curcuma longa | Root | 200 mg |
| 3 | Shallaki | Boswellia serrata | Extract | 100 mg |
| 4 | Pippali | Piper longum | Fruit | 25 mg |
| 5 | Maricha | Piper nigrum | Fruit | 25 mg |
Methods
Study Design
The current study was a prospective, open label, outpatient drug trial of Rumogin 5, conducted at Planet Ayurveda. 40 Patients of either gender, aged between 35 and 65 years, were diagnosed with rheumatoid arthritis (RA). All the 40 patients, who were selected for the trial study, were divided into two groups of 20 each i.e. group A and group B. All the patients were screened in the OPD of Planet Ayurveda during the study period. A thorough medical history, general physical examination, and rheumatologic assessment were documented by the assigned Ayurvedic specialist. Subsequently, all patients were examined by the expert at every visit during the trial.
Clinical Assessment
The study involved the analysis of 40 patients exhibiting symptoms of rheumatoid arthritis (RA), who were diagnosed as RA-positive through blood tests. Symptomatic evaluation and blood tests were conducted on all the patients. Patients had been suffering from morning stiffness, body aches, tenderness and swelling in both wrist and knee joints and walking difficulties for the past 6-9 years. Some patients had shown symptoms like pain and swelling at both shoulders and both elbow joints. All the patients underwent blood tests including haemoglobin, ESR, RA factor, C-reactive protein, SGOT and SGPT. All blood parameters were measured and documented for all the participants. There was no history of previous surgeries/ addiction/drug allergy reported by patients.
Other Diagnostic Criteria
The patients were diagnosed by other health concerns such as:
- Eyes: Discomfort, dryness, inflammation, redness, light sensitivity and difficulty seeing clearly.
- Mouth: Irritation, dryness, gum inflammation or infection.
- Skin: Rheumatoid nodules, which are small lumps beneath the skin, typically found over bony areas.
- Lungs: Scarring and inflammation that may cause difficulty in breathing and results in lung disease.
- Blood Vessels: Inflammation of blood vessels that can cause damage to nerves, skin and other organs.
- Blood: A reduced count of red blood cells.
- Heart: Inflammation that can harm the heart muscle and its surrounding tissues.
RumoGin 5 Capsules
Recommendations/Suggestions By Ayurvedic Expert To Patients
Self-Care
A balanced diet, regular exercise and mental well-being are essential for overall health and managing RA. So, Ayurveda experts advise all the patients to set health goals.
Diet
All patients were advised to follow a balanced, nutritious diet, as it supports overall health and helps in maintaining a healthy weight.
Daily Movement
Participants were encouraged to make movement in everyday routine.
Balancing Activity With Rest
All patients were recommended to stay physically active even during flare, to get relieved from pain and swelling.
Treatment Details
Treatment Period
2 months treatment.
Follow Up
The cases were followed up every 14 days up to 2 months to assess the improvement in all the parameters.
Dosage Of Rumogin 5
1-2 capsules, taken once or twice daily.
Observations And Result
Assessment Of Symptoms
Symptomatic assessment was done after the completion of treatment. Symptoms like joint pain, inflammation, pain at rest, tenderness and fever were completely relieved in both the groups. There was moderate reduction in morning stiffness and joint movement restriction and the results are depicted in table 2.
Table 2 Number Of Patients Exhibiting Rheumatoid Arthritis Symptoms
| Symptoms | Group A (n=20) BT | Group A AT | Group B (n=20) BT | Group B AT |
|---|---|---|---|---|
| Joint Pain | 20 | - | 19 | - |
| Swelling | 18 | - | 19 | - |
| Stiffness Upon Waking | 16 | 2 | 15 | - |
| Pain At Rest | 12 | - | 10 | - |
| Tenderness | 17 | - | 14 | 2 |
| High Temperature | 8 | - | 5 | - |
| Joint Movement Restriction | 12 | 3 | 13 | 1 |
| Loss Of Appetite | 13 | 2 | 9 | 1 |
After completing the 2 months treatment, there was a significant improvement in the clinical parameters, as shown in table 3. All the complaints of patient were relieved and all the parameters were to normal range. No adverse effects were reported in any of the cases.
Table 3 Incidence Of Clinical Investigations
| Investigations | Group A BT | Group A AT | Group B BT | Group B AT |
|---|---|---|---|---|
| ESR | ++++ | - | ++++ | - |
| RA Factor | +++ | + | ++ | - |
| C-Reactive Protein | ++ | - | +++ | - |
| SGOT | +++ | - | ++++ | + |
| SGPT | ++ | - | ++ | - |
Discussion
In this study, Rumogin 5 was selected for the clinical trial. It contains five key herbs, which are known for their anti-inflammatory, pain relieving and antioxidant properties. All these powerful herbs are essential for management of RA. Rumogin 5 is a potent formulation that has been shown to be safe and effective in providing relief to arthritis patients. This formulation was prepared from different parts of plants that are used in traditional medicine for a variety of purposes such as reduction of pain, reduction of inflammation and fever reducing activity. The individual characteristics of this study reveals that RA can begin at any age, but incidence increases with age. It clearly shows the predominance of the disease in females. The clinical trial in this study reveals that all patients were found to have improved symptoms like joint pain, morning stiffness, tenderness in joints, and joint swelling. 90% of the patients experienced relief from rheumatoid arthritis symptoms, as assessed through symptomatic evaluation. Mild to moderate improvements can be seen through clinical investigations like ESR, RA Factor, and C - reactive protein, SGOT and SGPT. After 2 months of treatment with Rumogin 5, rheumatoid arthritis patients showed notable improvements, with no adverse effects reported in any case.
Conclusion
The results of this study indicate that Ayurvedic treatment, Rumogin 5; holds potential for effectively managing rheumatoid arthritis. In conclusion, our findings highlight the potential effectiveness and safety of Rumogin 5 in managing rheumatoid arthritis symptoms, offering a promising solution to the growing concern surrounding this disease.
Patient Perspective
The patients were happy with the treatment, the quality of their life was improved considerably. They enjoy a normal and healthy life.
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