Role of Curcuma Longa (Curcumin) in Cancer

CURCUMA LONGA: OVERVIEW

Curcuma longa (the ‘Haridra’ herb) is a medicinal plant -- and a rhizomatous household spice -- which has, since ancient times, been widely used as a very effective home remedy for treating a number of diseases. The dried ground rhizome of Curcuma longa is called ‘turmeric’ in English and ‘haldi’ in Hindi.

Curcuma longa has been in use for years as a hemostyptic agent, and also as a tonic, anti-diarrheal, carminative, hepatoprotective and a purifying agent. The herb also plays a crucial role in cancer management as it possesses anti-pyretic property, due to which spontaneous regressions have been reported in cancer patients with infections, fever, and bacterial lipopolysaccharoides.

In terms of Ayurveda, the description of the pharmacodynamics of Curcuma longa is as follows: Rasa - tikta and katu, Guna - rukhsha and laghu, Virya - ushna, Vipak - katu and Doshaghnata – tridoshshamak.

The great sage Charaka has given the following classification of the Curcuma longa herb:

• Lekhaniya - a scrapping herb
• Varnya - complexion improving herb
• Vishaghna - anti-toxin, and
• Kusthaghna - anti-dermatosis.

Broadly speaking, Curcuma longa has been used through the ages as a remarkable 'herbal cortisone' and 'herbal aspirin.' It is also known for relieving inflammation and discomfort linked to a wide range of infections and autoimmune diseases.

ROLE OF CURCUMA LONGA IN CANCER MANAGEMENT

Curcuma longa is a short-stemmed perennial herb (of the ginger family, Zingiberaceae), with anti-inflammatory, anti-tumour and anti-cancer properties. Since chronic inflammation is believed to be one of the main causes of cancer formation, Curcuma longa can play a very important role in the management of cancer.

Curcumin Capsules of Planet Ayurveda are packed with standardized extract of Curcumin, a principal compound of turmeric.

The noteworthy anti-cancer property of the herb is a result of the presence of ‘Curcumin’ which is the key ingredient of Curcuma longa. According to several reports, Curcumin has an excellent anti-cancer potential, and it also evidently possesses the capability of free radical scavenging activity as well as inhibition of lipid peroxidation. In addition to Curcumin, two other ingredients of Curcuma longa -- Turmerone and polysacchrides -- also play a substantial role in anti-cancer activity.

Curcumin, in particular, can suppress the tumor angiogenesis; thereby triggering the much-required regression in the tumor metastatic growth. For the benefit of patients with external cancerous lesions, the ethanol extract of turmeric, together with the ointment of Curcumin, can reportedly produce incredible symptomatic relief. Curcumin also protects the body from HPV (human papillomavirus) which is one of the chief causes of cervical cancer. Moreover, turmeric oil and turmeric oleoresin can have a therapeutic effect on the patients suffering from oral submucous fibrosis (SMF).

In proof of the effective of Curcumin in managing cancers, research in recent times has revealed that Curcumin can suppress the transformation, proliferation and metastasis of tumors. It also has proven protective and therapeutic effects against skin cancer, blood cancer, and cancers of the lung, oral cavity, pancreas and intestinal tract.

The effectiveness of Curcumin in cancer management has come to the forefront because of the consistent capability of Curcumin to inhibit (suppress/block) NFkB (nuclear transcription factor kappa beta) which plays is one of the main reasons for inflammation and has a major role in most diseases, including cancer, arthritis, diabetes, cardiovascular disease, neurological diseases (like Alzheimer's), pulmonary diseases, and autoimmune diseases.

CHEMICAL COMPOSITION OF CURCUMA LONGA

The chemical composition of Curcuma longa comprises:

• Turmerin (a water-soluble antioxidant peptide)
• Curcuminoids including curcumin
• Essential oils (such as atlantones, turmerones, and zingiberene).

Curcumin has a low molecular weight. It is responsible for the yellow colour of turmeric, and forms a reddish-brown salt with alkali. It is soluble in ethanol, alkali, acetic acid, ketone, and chloroform.

Besides Curcumin, the other constituents of Curcuma longa include:

• Minerals (3.5%)
• Fat (5.1%)
• Protein (6.3%)
• Carbohydrates (69.4%)
• Moisture (13.1%).

ANTI-CANCER PROPERTY OF CURCUMA LONGA

In a nutshell, the mechanisms via which Curcuma longa gets its anti-cancer property are:

• Anti-oxidant property
• Anti-mutagenic activity
• Free radical scavenging activity
• Blocking of NFkB.

In terms of anti-cancer action, Curcumin -- and turmeric oil -- has attracted a lot of attention in recent times because of its ‘chemoprevention’ potential. The term ‘chemoprevention’ can be defined it as a ‘preventive modality’ which involves the use of natural or synthetic agents for stopping, slowing down, reversing or preventing the development of cancer.

The 'chemoprevention' potential of the Curcumin ingredient in Curcuma longa herb is largely based on the easy accessibility of the herb, along with its safety of use, mechanism of action, and multi-targeted anticancer effects. As a result of its 'chemoprevention' potential, Curcumin can be extremely beneficial for the improvement and enhancement of the quality of life of cancer patients.

Chemopreventive agents are categorized into three different subgroups, on the basis of their mode of action. Due to Curcumin's multiple mechanisms of action, it belongs to all the three subgroups of Chemopreventive agents, namely: Antioxidants, Antiproliferatives, and Carcinogen-blocking agents.

CURCUMIN: A COMPLEMENTARY ALTERNATE MEDICINE FOR CANCER CARE

Based on the implication of experimental data, it is apparent that Curcuma longa's Curcumin ingredient has proven benefits associated with each of the following three stages of cancer --- promotion, progression, and metastasis.

The beneficial effects of Curcumin at each stage of cancer are mediated through its ability to regulate diverse transcription factors, growth factors, protein kinases, inflammatory cytokines, and other enzymes.

The various notable aspects due to which Curcuma longa/Curcumin can be considered as a complementary alternate medicine for cancer care include:

• For supplementing anti-cancer treatment
• For reducing pain and complications related to cancer
• For reducing side-effects of radiotherapy and chemotherapy
• For preventing metastasis of cancer.

CONCLUSION

In the opinion of researchers, the anti-cancer properties of Curcuma longa make it one of the most important herbs which can be considered as an effective complementary and alternative medicine for the management and prevention of cancer, especially in India, from both basic and clinical perspectives. To sum up, the Curcumin constituent of Curcuma longa is an important polyphenolic compound which can effectively suppress, delay, or reverse cancer, one of the foremost causes of death in the world.

Planet Ayurveda recommends Cancer Care Pack for Cancer patients. Our Cancer Care Pack helps in fighting various types of cancer. The Cancer Care Pack has a combination of different herbs which work together in an optimal manner to fight cancer at the cellular level. This combo pack contains effective herbal remedies and classic herbs which support and strengthen the individual’s body to fight against the cancer affected areas. Read more...

Cancer Care Pack

Ayurvedic Treatment of Ewing sarcoma

Ewing sarcoma is a type of cancer that occurs in and around the bones, but most often begins in the leg bones and hipbones as well as in the arms, chest, spine and skull. It occurs rarely in the soft tissues of the legs, arms, abdomen, chest, neck and head. It can occur at any age and is rare but it most commonly develops during puberty when bones are growing rapidly.

Boys and young men are affected more frequently than girls and young women. The pelvis is the most common location followed in order by the femur, tibia, humerus and scapula. However, it can be found in any part of the body. It is 10 times more common in whites than in blacks. These ratios are consistent throughout the world.

WHAT ARE THE CAUSES OF EWING SARCOMA?

Research suggests that it is not related to exposure radiation or chemicals. It appears that the cell DNA changes after birth, leading to Ewing sarcoma.

WHAT ARE THE SYMPTOMS OF EWING SARCOMA?

People with ewing sarcoma complain of pain and sometimes notice as mass. Generally, the mass will continue to grow over the course of a few weeks to weeks. Sometimes, the tumor eats away the bone and causes a fracture.

• Pain, swelling or stiffness in the area of tumor for weeks or months.
• Constant low fever
• Bone pain that gets worse when a patient exercise or during night
• Limping because the legs hurt
• Weight loss
• Broken bones without an obvious cause
• If the tumor is near spine, paralysis or loss of bladder control.

DIAGNOSIS

Under the microscope, Ewing Sarcoma is characterised by small, round and blue cells. Primitive neuroectodermal tumors (PNET) are very molecularly related tumors that often arise outside of the bone and are treated the same as Ewing's sarcoma.

TREATMENT

Modern treatment includes multidrug chemotherapy as well as local disease control with surgery or radiation. Radiotherapy has been used for localised disease as the tumor has a unique property of being highly sensitive to radiation but the main drawback is that it recurs dramatically after sometime.

Surgery is performed is determined by how large the tumor is and how far it extends into surrounding tissues. The goal of surgery is the complete removal of the tumor but surgery is not successful in many cases.

AYURVEDIC TREATMENT FOR EWING SARCOMA

Ayurvedic treatment uses the inherent power of natural herbs to treat the disease. The herbs are 100% natural and safe. Ayurveda helps naturally in enhancing the body functioning in the natural way. The herbs for Ewing Sarcoma in Ayurveda help to stop abnormal growth of cells and help in regenerating normal healthy body cells.

Even in later stages of cancer, Ayurvedic treatment of cancer help in relieving unearthly pain and suffering.

Classical Ayurvedic texts have several references to cancer. Some terms have been used to describe the condition are general while other terms are more specific.

Cancer has been described as granthi (benign or minor neoplasm) and arbuda (malignant or major neoplasm). Both can be inflammatory or non-inflammatory based on doshas involved. Tridoshas cause excessive metabolic crisis resulting in proliferation.

The modern cancer therapy is known to be burdened by drug-induced toxic side effects. On the other hand, Ayurveda uses multiple herbs possessing great potential for a cancer cure. These herbal formulations work on multiple biochemical pathways and influence different organ systems all together and nourish the body as a whole by supporting body's defence systems.

Cancer Care Pack of Planet Ayurveda helps in fighting various types of cancer. It is a combination of different herbs which work in optimal manner to fight cancer at the cellular level. These herbal formulations help in total healing, reduces the side effects and cancer-associated complications.

Each herb contains multiple active principles that work synergistically thus produce therapeutic benefits and also lowers the risk of adverse effects thus avoids the need for supplemental therapy.

CRAB CARE PACK OF PLANET AYURVEDA CONSISTS OF

1. Ashwagandha Capsules
2. Curcumin Capsules
3. Kachnaar Guggul
4. Tulsi Capsules
5. Guggul Capsules
6. Chanderprabha Vati

1. Ashwagandha Capsules:

Ashwagandha herb plays a vital role in stress induced disorders including neurological disorders as it possesses a great anti-oxidant and anti-inflammatory properties. It helps to promote the overall well-being of the body and nourishes the brain to make the functioning of the brain quicker and sharper. Planet Ayurveda provides best of Ashwagandha benefits in Ashwagandha capsules.

2. Curcumin Capsules:

Because of rich medicinal properties, curcumin is widely used herb in case of cancer. Anti-oxidants present in the herb helps in reducing free radicals in the body. In many malignant cancers, curcumin is found to be very helpful.

3. Kachnaar Guggul:

Kachnaar Guggul is a natural product obtained from the mixture of kachnar bark (Bauhinia variegate), Amalki (Emblica officinalis), Haritaki (Terminalia chebula), Bibhaitaki (Terminalia bellerica), Ginger (Zingiber officinale), Black pepper (Piper nigrum), Pippali (Piper longum) and Varuna (Crataeva religiosa). Kachnaar Guggul helps to maintain cells and tissues healthy.

4. Tulsi Capsules:

Tulsi herb possesses strong anti-oxidant properties and it helps in removing free radicals from the body. This is a natural product obtained from pure tulsi extract (Ocimum sanctum).

5. Guggul Capsules:

Guggul Caspules of Planet Ayurveda are obtained from Guggul (Commiphora mukul). These capsules have anti-oxidant property and are useful in many health conditions. These capsules revitalise the cells and therefore rejuvenate them.

6. Chanderprabha Vati:

This tablet contains mixture of different herbs like Shilajit (Asphaltum), Sugar, Vacha (Acorus calamus), Haridra (Curcuma longa), Karpoor (Cinnamomum camphora), Amla (Emblica officinalis) etc. These tablets have calming effect on the entire body. It is one of the most adaptogen and stress busters that cause relaxation.

Planet Ayurveda offers a wide range of herbal supplements that are 100% pure, herbal and are prepared through a series of effective and stringent tests to assure their quality.

Early detection is believed to be the key factor in combating cancer effectively along with herbal remedies.

Ayurvedic Treatment for Cancer of Urinary Bladder

Cancer – This word is enough to scare anyone. It seems like life has come to an end, one feels like there is no hope in life. No doubt cancer is an ugly disease but if one has strong will then you can overcome anything. Here we are talking about cancer of urinary bladder and will also discuss all the aspects of disease in detail.

Ayurveda is the new ray of hope to manage this problem. According to Ayurveda, cancer is called as Granthi Roga. Cause of cancer in Ayurveda is imbalance of tri doshas - vata, pitta and kapha. To manage this problem use of herbs is fruitful since ages. Herbs help to stop the growth of cancer cells and encourage the growth of healthy cells.

WHAT IS URINARY BLADDER CANCER?

As its name indicates it is a type of cancer of the bladder. Bladder is the part of excretory system and its role is to store the urine before urinating. Urinary bladder is made up of different layers. Generally cancer of urinary bladder starts with the innermost layer which is called Urothelium or transitional epithelium. When cells in the urinary bladder start to grow uncontrollably, more cancer cells develop, so as to form a tumor and spread to other areas of the body.

SYMPTOMS ASSOCIATED WITH URINARY BLADDER CANCER

Bladder Cancer Signs and Symptoms may include:

• Blood in Urine (Hematuria) - Urine may appear bright red or cola colored. Or urine may appear normal, but blood may be detected in a microscopic examination of the urine.
• Frequent and painful urination.
• Back pain.
• Pelvic pain.
• Feeling tired or weak
• Loss of appetite and weight loss
• Swelling in the feet

Note - Make an appointment with your doctor if you have any signs or symptoms that worry you, such as blood in your urine.

CAUSES

Exact cause of bladder cancer is not known. It can be linked to smoking, a parasitic infection, radiation and chemical exposure.

RISK FACTORS

• Increasing age 
• Smoking
• Being white 
• In males
• Exposure to certain chemicals
• Previous cancer treatment
• Treatment with anti-cancerous drugs
• Taking a certain diabetes medication
• Chronic bladder inflammation
• Personal or family history of cancer 

PLANET AYURVEDA'S TREATMENT FOR CANCER OF URINARY BLADDER

Planet Ayurveda offers different formulations like tablets, capsules, and powders etc. which are prepared from pure herbs. These medicines are free from any chemical, preservatives and have no side effects. They provide herbal medicines for the management of urinary bladder cancer which are explained below.

HERE ARE THE DETAILS OF MEDICINES

1. Boswellia-Curcumin

These are pure herbal capsules obtained from a combination of herbs which are very well known for their actions - Shallaki (Boswellia serrata) and Curcumin (Curcuma longa). These herbs possess anti-inflammatory properties and manage the symptoms associated with urinary bladder cancer. These herbs are very helpful in various health problems.

Dosage - 2 capsules twice daily.

2. Varunadi Vati

This is another herbal preparation which is prepared from combination of various herbs – Punarnava (Boerhavia diffusa), Varun (Crataeva nurvala), Gokshura (Tribulus terrestris), Shudha guggulu (Comniphora mukul).

Benefits - This herbal formulation is very useful in case of various health problems like kidney problems, urinary tract infection etc. Punarnava has diuretic, emetic, laxative and stomachic properties. Varun has the property to remove toxins from the body and manage overall kidney functions. This property to manage all the symptoms associated with Urinary bladder cancer.

Dosage - 2 tablets thrice daily.

3. Kanchnaar Guggul

These are herbal tablets prepared form different herbs which are listed below:

• Kanchnaar Bark (Bauhinia variegate)
• Amalaki (Emblica officinalis)
• Haritaki (Terminalia chebula)
• Bibhitaki (Terminalia bellerica)         
• Ginger (Zingiber officinale)    
• Black Pepper (Piper nigrum) 
• Pippali (Piper longum)           
• Varuna (Crataeva religiosa)

Benefits - All these herbs are packed with various medicinal properties. These are helpful to manage all three doshas in the body. This formulation has antioxidant properties which help to remove free radicals from the body. It enhances the immunity of body and helps the body to fight against various types of cancers.

Dosage - 2 tablets thrice daily.

4. Ashwagandha Capsules

These are pure herbal capsules obtained from extract of herb Ashwagandha (Withania somnifera). This herb has great medicinal values which are used to maintain overall wellbeing. It also gives strength and immunity to body.

Dosage - 1 capsule twice in a day with plain water after meals.

5. Shilajit Capsules

Shilajit capsules are prepared from pure natural compound Shilajit (Asphaltum). It has great medicinal properties and has the ability to improve the immune system. It also has antioxidant properties which help to remove the toxins from the body. It helps to maintain overall health and wellbeing.

Dosage - 1 capsule twice in a day with plain water after meals.

6. Trin Panchmool Ghan Vati

The Ayurvedic herbal formulation is in tablet form which is prepared from five herbs which are listed below.

• Kusha (Desmostachya bipinnata)
• Darbh (Cynodon dactylon)
• Kasha (Saccharum spontaneum)
• Shara (Ceratophyllum submersum)
• Ikshu (Saccharum officinarum)

Benefits - The herbs used in this formulation are useful in renal disorders. These herbs increase the urine quantity and balance all three doshas i.e. vata, pitta and kapha. It helps to eliminates excess water, helps in burning sensation and gives strength to the renal system. This formulation have the ability to improve immunity and provides strength to the body to fight against various disease condition. It has diuretic action.

Dosage - 2 tablets twice daily.

7. Cruel Plus Capsules

This formulation helps to manage all symptoms associated with the urinary bladder cancer.

Dosage - 1 capsule twice daily.

8. Sachets

Mixture of Following:-

• Rajat Bhasma - 5 gm
• Praval panchamrit - 5 gm
• Jahar Mohra Pishti - 5 gm
• Punarnava mandur - 10 gm
• Heerak Bhasma - 300 mg
• Yashad Bhasma - 5 gm
• Giloy Satv - 10 gm
• Swarn Makshik Bhasma - 5 gm
• Akik Pishti - 5 gm
• Kamdudha ras - 5 gm
• Cancer Gaj Kesri Ras - 5 gm
• Cancer Vidhwansan Ras - 5 gm
• Raj Mrigank Ras - 2 gm
• Loknath Ras - 5 gm
• Trailokyachintamani Ras - 2 gm
• Hemgarbhpotli Ras - 2 gm
• Swarn Basant malti Ras -2 gm
• Yavkshaar - 10 gm
• Mooli Kshaar - 10 gm
• Sajji Kshaar - 10 gm
• Shwet Parpati 5 gm 
• Hazral Yahood bhasma - 5 gm
• Trivikram Ras - 2 gm

Mixture of all these, make 60 sachets, give 1 sachet twice daily with honey after meals.

WHY SHOULD ONE GO FOR PLANET AYURVEDA?.

• All the products are 100% pure.
• Efficacy of the herbs is checked in the labs before making any herbal formulation.
• Products are free from chemicals, preservatives, starch and any color.
• All the products are manufactured under the guidance of highly experienced MD Ayurveda doctors.

Contact my assistant to provide you the costing / ordering and delivery information at - costing.planetayurveda@gmail.com or call at +91-172-5214030