Ayurvedic Remedy for Fatty Liver Relief: Heal Naturally with Yakrit Plihantak Churna

Abstract

Yakrit Plihantak Churna is an amazing preparation for Fatty liver diseases. Fatty liver disease is a condition where fat accumulates in the liver and are of two main types i.e. AFLD (Alcoholic fatty liver disease) and NAFLD (Nonalcoholic fatty liver disease). Yakrit Plihantak Churna contains herbs like Bhumi Amla (Phyllanthus niruri), Kalmegh (Andrographis paniculata), Bhringraj (Eclipta alba), Sharpunkha (Tephrosia purpurea), Kaasni (Cichorium intybus), Katuki (Picrorhiza kurrao), Makoy (Solanum indicum) and Punarnava (Boerrhavia diffusa). All these herbs work synergistically and assists in sustaining good health of the hepatic system. Herbal Churna (Yakrit Plihantak) can potentially have a positive effect on fatty liver by aiding liver detoxification, reducing inflammation, improving lipid metabolism and promoting weight loss.

In this case, the effect of Ayurveda intervention in fatty liver is reported. The hepatoprotective effects of the herbal formulation Yakrit Plihantak Churna are well established in a study among 50 adult patients of either sex of different age and divided into 5 groups i.e. Group Ⅰ (n=10), group Ⅱ (n=7), group Ⅲ (n=9), group Ⅳ (n=11) and group Ⅴ (n=13) respectively. All these cases of nonalcoholic fatty liver disease (NAFLD) reported to the OPD of Planet Ayurveda with different signs and symptoms.

The current literature supports the growing importance of the usage of herbal Churnas in the management of liver diseases due to their efficacy and very low incidence of adverse effects. The evidence collected from preclinical and clinical studies supports the use of this herbal Churna in symptomatic improvement due to its potential anti-oxidant and anti-inflammatory effects. The health of all the patients got improved and helped in aiding the management of NAFLD. Churna formulation (Yakrit Plihantak Churna) from Planet Ayurveda is well tolerated and has shown a good safety profile. So, it is a favorable herbal choice for the management of liver diseases due to various etiologies.

Introduction

Fatty liver disease refers to a condition in which excess fat accumulates in the liver cells affecting metabolic function of the liver leading to liver damage. A healthy liver comprises a small amount of fat and it becomes concerning when fat reaches more than 5 % to 10 % of the liver’s total weight. There are two major forms of fatty liver disease: Alcoholic Fatty Liver Disease (AFLD) and Nonalcoholic Fatty Liver Disease (NAFLD). NAFLD is now more familiar than AFLD around the World and is currently estimated to attack 38 % of the global population.

Herbal medicines have gained popularity as potential therapeutic agents for the prevention and treatment of non alcoholic fatty liver disease due to their efficacy and low side effects. The study involved 50 patients and all the selected patients diagnosed with NAFLD. Patients showed symptoms like fatigue, loss of appetite, constipation, nausea, flatulence and abdominal pain. Timely detection and lifestyle modifications play a crucial role in successful management of fatty liver. One of the most effective remedies is Yakrit Plihantak Churna by Planet Ayurveda.

Objective Of The Study

To study the positive effect of Yakrit Plihantak Churna in patients of Nonalcoholic Fatty Liver Disease (NAFLD).

Raw Materials

Ingredients used in Yakrit Plihantak Churna are as follows (Table 1).

S.No.	Herbs Used	Latin Name	Parts Used	Quantity
1.	Bhumi Amla	Phyllanthus niruri	Whole	60 gm
2.	Kalmegh	Andrographis paniculata	Whole	20 gm
3.	Bhringraj	Eclipta alba	Whole	20 gm
4.	Sharpunkha	Tephrosia purpurea	Roots	20 gm
5.	Kaasni	Cichorium intybus	Roots	20 gm
6.	Katuki	Picrorhiza kurrao	Stem	20 gm
7.	Makoy	Solanum indicum	Whole	20 gm
8.	Punarnava	Boerrhavia diffusa	Roots	20 gm

Yakrit Plihantak Churna

Methods

The present study is a clinical trial involving 50 patients from various age groups who attended the OPD of Planet Ayurveda, Mohali. Patients with symptoms suggestive of NAFLD were treated with Yakrit Plihantak Churna with prescribed dosage.

1. Grouping

50 patients were chosen and assigned to 5 groups i.e. group Ⅰ (n=10), group Ⅱ (n=7), group Ⅲ (n=9), group Ⅳ (n=11), group Ⅴ (n=13) respectively. The study was conducted among 50 patients, all diagnosed with NAFLD and commonly detected by blood liver function tests and lipid profile assessments. Patients with NAFLD have such signs and symptoms are fatigue, loss of appetite, constipation, nausea, flatulence and abdominal pain.

Recommended Dosage

Yakrit Plihantak Churna was administered to every patient with a dose of 1/2 to 1 teaspoonful twice a day, taken with plain water or fruit juice for a period of 3 months. Administration was after the meals.

Lifestyle Changes

Along with the proper dosage of Yakrit Plihantak Churna, patients were also advised to make lifestyle changes during the treatment period of 3 months. This may provide support, managing fatty liver primarily by lifestyle modifications like dietary changes, regular exercise, and yoga asana and weight management.

Quality of Life

Quality of life assessment was done using the liver disease questionnaire from all the patients as baseline characteristics (%) and symptoms before the start of treatment, data is depicted in graph 1.

Graph 1: Assessment of quality of life before treatment

2.Screening Methods

All patients included in this study were examined thoroughly and data was recorded systematically. Various Laboratory and Ayurveda variables were assessed. Clinical trials were carried out over a period of 3 months and biochemical parameters were measured and assessed before starting the treatment, as depicted in table 2.

Table 2: Laboratory findings of patients before treatment:

Comprehensive Metabolic Panel	Group Ⅰ (n=10)	Group Ⅱ (n=7)	Group Ⅲ (n=9)	Group Ⅳ (n=11)	Group Ⅴ (n=13)	Ref. Range
LFT (SGOT/SGPT)	40–45	45–50	50–55	55–60	60–65	<45 U/L
Cholesterol	190–220	220–250	250–280	280–310	310–340	<200 mg/dL
HbA1c	7.0–7.5	7.5–8.0	8.0–8.5	8.5–9.0	9.0–9.5	<5.7 % (normal)
Urine Albumin	60–87	70–80	80–90	90–100	110–120	<55 g/L

Observations and results: Wellbeing/ Wellness Assessment

The overall values of selected patients improved significantly after completion of treatment. Before beginning the treatment, the quality of life score was poor in all the parameters selected. Following treatment, the quality of life score showed improvement in all the patients and experiencing the progress which is depicted in graph 2.

Graph 2: Assessment of quality of life after treatment

Influence on biochemical parameters: Biochemical measures were evaluated after 3 months of treatment, data is presented in table 3.

Table 3: Laboratory findings of patients after treatment

Comprehensive Metabolic Panel	Group Ⅰ (n=10)	Group Ⅱ (n=7)	Group Ⅲ (n=9)	Group Ⅳ (n=11)	Group Ⅴ (n=13)	Ref. Range
LFT (SGOT/SGPT)	30–34	34–37	37–41	41–47	47–50	<45 U/L
Cholesterol	120–140	140–155	155–180	180–190	190–205	<200 mg/dL
HbA1c	6.8–7.3	7.3–7.7	7.7–8.1	8.1–8.7	8.7–9	<5.7 % (normal)
Urine Albumin	48–52	52–57	57–62	62–78	78–95	<55 g/L

Following 3 months of Ayurveda treatment, significant improvements were noted in all the parameters and fell within the normal range. Nevertheless, the effect was most noticeable on Cholesterol levels and liver function.

Discussion

In this investigation, we have treated patients with nonalcoholic fatty liver diseases (NAFLD). A total of 40 patients participated in the study and were treated with administration of Yakrit Plihantak Churna and advised with some lifestyle changes. The study showed that Yakrit Plihantak Churna is effective and showed 45% improvement in symptoms of fatigue, 58% control over appetite, 47% improvement in constipation, 39% improvement in feeling of nausea and 77% reduction in abdominal pain. Liver function evaluation showed significant improvement and reduction was noted in SGOT/SGPT values. These effects could be due to pharmacological activities of ingredients of Yakrit Plihantak Churna. Studies have shown that all the ingredients have properties like hepatoprotective, anti-inflammatory, anti-oxidant and anti NAFLD effects. The study also showed significant improvements in the parameters of cholesterol, as all the cholesterol levels are reduced and fall in the normal ranges. Following one month of treatment, both subjective and objective parameters showed a significant response and the condition of all the selected patients got better. These findings emphasize the usefulness of prescribed treatment in controlling non-alcoholic fatty liver disease.

Conclusion

According to the findings, the study demonstrated that Yakrit Plihantak Churna was hepatoprotective and is a known polyherbal formulation which contains powdered herbal mixtures. It is well tolerated in the study population after treatment for 3 months. Significant improvements were seen in clinical signs and symptoms and laboratory parameters of liver function. Herbal Churna from Planet Ayurveda showed promising results in the management of NAFLD and is safe to use. Assessment and biological effect of Yakrit Plihantak Churna on fatty liver will be beneficial and the outcomes observed in this case are promising. Based on these Ayurveda interventions for fatty liver, we can suggest that it offers a natural, effective approach to manage and prevent liver issues. Through understanding herbal formulations for liver health, using herbal treatments and maintaining lifestyle practices, individuals can bring balance to their liver and ensure long-term protection. With this approach, it not only targets the symptoms of fatty liver but also works to treat its root cause, offering a long-term solution to liver health and overall well-being.

Patient Perspectives

The patients were satisfied with the treatment given and showed improvement in digestion, appetite, lethargic condition and all the selected parameters. After 3 months of the treatment, the patients were feeling energetic and actively doing all daily activities.